The invention relates to an application for luteolin-7-diglucuronide in preparation of a medicine for treating degenerative retinal diseases. According to the application, a mouse model with retinal light injuries is used for simulating a common pathological link during various degenerative retinal disease occurrence processes, namely, photoreceptor cell death, the effects of resisting photoreceptor cell death and preventing the occurrences of degenerative retinal diseases of luteolin-7-diglucuronide are researched, and the result indicates that the compound is capable of maintaining the form of the outer core layer of the retina, preventing the injuries of the outer core layer of the retina, preventing the thickness reduction of the outer core layer of the retina, effectively inhibiting the photoreceptor cell death, and remarkably improving the degenerative retinal diseases, and therefore, luteolin-7-diglucuronide can be used for preparing the medicine for treating degenerative retinal diseases.