The invention discloses nano lamination composite extrusion equipment capable of guaranteeing the wall thickness of a pipe blank. The nano lamination composite extrusion equipment comprises plasticizing material supplying devices, a converging device, a composite lamination generator and a pipe blank mold head which are connected in sequence, wherein n plasticizing material supplying devices are arranged; the converging device is provided with n inlets and a flat outlet; the outlet of the converging device is provided with n regions along the thickness direction; the converging device is internally provided with a first melt channel which is respectively communicated with the inlets and corresponds to the flat outlet region; each inlet of the converging device is connected with a plasticizing device; the composite lamination generator is formed by connecting a plurality of composite molds; the composite lamination generator and the pipe blank mold head are connected by a first transition mold and a second transition mold. The nano lamination composite extrusion equipment provided by the invention has the advantages that after the first transition mold and the second transition mold are arranged, two semicircular melts are equal in thickness by two same layers, thereby guaranteeing the quality of the pipe blank.