The embodiment of the invention relates to the field of chromatographic analysis, and especially relates to a chromatogram processing method and a chromatographic instrument. The chromatogram processing method comprises: obtaining a deleting area appointed by a user; determining whether the deleting area comprises the top point of a peak; and deleting the peak if the deleting area comprises the top point. The chromatographic instrument comprises a receiving unit, a determining unit and an execution unit, the receiving unit is used to obtain the deleting area appointed by a user, the determining unit is used to determine whether the deleting area comprises the top point of a peak, and the execution unit is used to delete the peak if the deleting area comprises the top point. According to the chromatogram processing method and the chromatographic instrument provided by the embodiment of the invention, once the condition is satisfied that the top point of a peak is in the deleting area appointed by a user, according to the method, the peak containing the top point can be directly deleted, so that the operation of the user is simple on the one hand, and the realization complexity of technology is reduced on the other hand.