The invention provides an interrupt processing method and device and an interrupt controller. The method includes the steps that a CPU receives an interrupt request sent by the interrupt controller, executes interruption corresponding to the interrupt request and writes in a first value in the interrupt controller, wherein the first value is used for indicating that the CPU receives the interrupt request; after the CPU executes the interruption, the CPU writes in a second value in the interrupt controller, wherein the second value is used for indicating that the CPU finishes execution of the interruption. According to the interrupt processing method and device and the interrupt controller, the problems that in the relative technique, an interrupt controller uses much logic and occupies a large area, by means of asynchronous sampling, loss of an interrupt signal is avoided, software procedures are simplified, and accordingly the effects that amount of the logic of the interrupt controller is reduced and the area is saved are achieved.