The invention relates to the field of fine chemistry, and provides a fluorine-containing alkynol compound and a synthesis method thereof in order to solve the problem of environmental pollution and realize green construction of a fluorine-containing organic compound. The method comprises the following steps: under inert gas protection, adding trifluoroacetophenone and alkyne-terminated compound into a dried container; in the joint action of a catalyst, organic base and phosphine ligand, heating to 10-100 DEG C by taking water as a solvent; stirring for 8-24 hours, and then cooling to room temperature; extracting with ethyl acetate; drying the organic phase, and separating and purifying through silica-gel column chromatography to obtain the fluorine-containing alkynol compound. The method provided by the invention can be performed in a water phase, reduces the environmental pollution, is an environment-friendly green synthesis method conforming to the development of modern chemistry, and has an important value in industrial application; meanwhile, the synthesis method provided by the invention is simple and convenient to operate, the reaction conditions are mild, and the yield is relatively high.