The invention discloses a reaction system for extraction of a heated solvent of coal and a reaction method. The reaction system comprises a plurality of sets of premixing and stirring devices which are arranged to be in parallel. The outputs of the premixing and stirring devices are communicated with inlets of tubular-type reactors, and transportation of materials is achieved through a pressurized feeding device. The outlets of the tubular-type reactors are communicated with a plurality of sets of post-treatment devices which are arranged to be in parallel and used for separating the material liquid after reaction. The system can stir materials in different phases through the premixing and stirring devices, and achieves uniform contact and flow of the materials in different phases in a reaction pipe. The high efficiency and continuous operation of the system can be ensured. Through alternate operation of the plurality of sets of premixing and stirring devices and post-treatment devices, the continuous operation of operating processes can be achieved. The system has advantages of low requirements to devices, short technological process and low device cost.