The invention relates to an eccentric transmission shaft. The eccentric transmission shaft comprises a shaft body, a first shaft head and a second shaft head, wherein the first shaft head and the second shaft head are arranged at two ends of the shaft body; the axes of the first shaft head and the second shaft head are coaxial and parallel to the axis of the shaft body; the first shaft head, the second shaft head and the shaft body adopt a split structure; the first shaft head and the second shaft head are respectively fixed on the shaft body through fastening pieces. The first shaft head and the second shaft head are respectively fixed on a first clamping base and a second clamping base; shaft neck holes parallel to the axes of the first shaft head and the second shaft head are formed in the first clamping base and the second clamping base respectively; axial clamping blocks and axial opening grooves are arranged on the hole walls of the shaft neck holes; coaxial through holes and thread holes are respectively formed in two sides of the opening grooves; two ends of the shaft body are respectively provided with shaft necks matched with the shaft neck holes; clamping grooves matched with the axial clamping blocks are formed in the shaft necks. The eccentric transmission shaft adopts the split structure, so that when the eccentric transmission shaft is worn, all that is needed is to replace the first shaft head or the second shaft head instead of replacing the whole eccentric transmission shaft, so that the cost is reduced.