The invention relates to a traditional Chinese medicine composition for gallstone and prostatic hyperplasia, belonging to the technical field of Chinese medicinal herbs. The composition is composed of the following active pharmaceutical ingredients in parts by weight: 55-65 parts of rhizoma atractylodis, 55-65 parts of rhizoma alismatis, 25-35 parts of radix curcumae, 15-25 parts of radix salviae miltiorrhizae, 5-15 parts of raw hawthorn, 25-35 parts of lotus leaf, 25-35 parts of chickens gizzard-skin, 25-35 parts of semen cassiae torae, 25-35 parts of radix clematidis and 5-15 parts of dried orange peel. The composition has the characteristics of accessible materials, simple manufacturing process, low cost, high practicality, small dosage, low content of harmful ingredients, no toxic or side effect, obvious curative effect and the like.