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发明公开
CN103357071A 软骨组织培养材料 无效 - 撤回

软骨组织培养材料
摘要：
本发明提供一种能够制作状态与存在于生物体内的软骨组织大致相同的软骨组织并且体积大的软骨组织培养材料。一种用于软骨再生的包含软骨细胞的软骨组织培养材料，其特征在于，其为浓度为1×107个细胞/cm3～1×109个细胞/cm3的软骨细胞与生物体吸收性高分子的混合物，最小部的厚度为2.2mm～100mm，软骨细胞与生物体吸收性高分子的体积比为7:3～9.5:0.5，糖胺聚糖产生量为每单位细胞0.001ng～0.2ng，I型胶原与II型胶原的含有比为10:90～1:99，并且每1mg组织干重含有0.01mg～0.65mg的II型胶原。
摘要（英）：

Provided is a cultured cartilage tissue material which enables formation of cartilage tissue being substantially the same as the cartilage tissue actually in the living body, and which is large in volume. The cultured cartilage tissue material is to be used for cartilage regeneration and comprises chondrocytes, and is a mixed body of chondrocytes in a concentration of 1 x 10 <7> to 1 x 10 <9> cells/cm <3> , and a bioabsorbable polymer. A thickness of the thinnest part of the cultured cartilage tissue material is 2.2 to 100 mm. A volume ratio between the chondrocytes and the bioabsorbable polymer is 7:3 to 9.5:0.5. A production amount of glycosaminoglycan is 0.001 to 0.2 ng per unit cell. A content ratio between type I collagen and type II collagen is 10:90 to 1: 99. A content of type II collagen is 0.01 to 0.65 mg per 1 mg of dry weight of tissue.

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