The invention discloses an optical fiber sensing packaging method used for modulating Brillouin scattering stain/temperature sensitivities, and belongs to the technical field of an optical fiber sensing network. According to the method, through theoretical analysis and numerical calculation, the characteristics of the influence of relevant parameters of an optical fiber structure on the responding relationship of Brillouin frequency shift amount and strain sensitivity at constant temperature and the characteristics of the influence of relevant parameters of the optical fiber structure on the responding relationship of Brillouin frequency shift and temperature sensitivity under constant strain, and the attributes of different inner sheath packaging structures are respectively obtained, and the attributes of the different inner sheath packaging structures include a material thermal expansion coefficient, the interval between an inner sheath and a bare optical fiber, and the effect of modulating the Brillouin scattering stain/temperature sensitivities.