The invention discloses a medicine for treating three-highs and a preparation method thereof. The medicine comprises the following ingredients: 2g of fructus evodiae, 2g of rhubarb, 2g of fleece-flower root, 2g of rhizoma alismatis, 2g of radix salviae miltiorrhizae, 2g of yam and 1g of musk. The medicine disclosed by the invention adopts a plurality of traditional Chinese medicine raw materials and can effectively reduce blood pressure, blood fat and blood sugar, a plantar dressing treatment method is adopted at the same time, the method is an external treatment based on traditional Chinese medicine, the medicine provided by the invention is applied to the Yongquan acupoints at the feet of a human body to regulate the balance mechanism, eliminate thrombus, reduce cholesterol, soften blood vessel, adjust the internal organ functions, regulate blood pressure, restore the yin-yang balance of a human body and reduce the three-highs symptoms of the human body, and the medicine has no toxic or side effects and relieves the pain of people after being used.