The present invention relates to an analytical method of a sandstone diagenetic process and pore evolution. The method comprises the steps of: (1) detecting reservoir rock composition parameters, reservoir diagenetic fluid characteristic parameters, regional characteristic parameters and burial manners of a simulated region; (2) proportioning sandy mixed samples, muddy samples and diagenetic fluids for simulation according to the detection results in step (1); (3) placing the samples prepared in the step (2) in a reservoir diagenetic simulation device; (4) conducting simulation experiments; and (5) performing reservoir microscopic characteristic analysis for obtained simulation diagenetic samples, wherein the analysis includes: rock thin section authentication, rock sample scanning electron microscope analysis, X-ray diffraction quantitative analysis for the total amount of clay minerals in sedimentary rocks and common non-clay minerals, and analysis and evaluation of reservoir diagenetic evolution process based on results.