The invention provides a retractable multi-group longitudinal water seal photoelectric composite cable and a manufacture process thereof. Signal lines for transferring control signals, communication signals, optical signals and radio-frequency signals and power lines for transferring electric energy are compounded to form one cable, wherein the signal lines include multiple tightly-wrapped optical cables 1 and coaxial cables 4, the coaxial cables 4 are arranged among the multiple tightly-wrapped optical cables 1, and multiple shielding twisted pair cables 2 are arranged in the coaxial cables 4. Multiple tensile aramid fiber filling ropes 3 are arranged around the signal lines and a power line 5 and at the gap positions, water-stopping wrapping bands 6 with water-stopping bands are wound in layers among the multiple shielding twisted pair cables 2, water-stopping glue 7 is arranged at the positions of twisting gaps of metal conductors and cabling and twisting sub-gaps, and a sheathed reinforcing layer 8 and an outermost polyurethane sheath 9 are arranged outside the twisted and cabled composite cable. The retractable multi-group longitudinal water seal photoelectric composite cable has the advantages of being tension-resisting, abrasion-resisting, and capable of resisting 4.5MPa longitudinal water pressure and being used in retractable mode and has multiple functions, and the trouble that multiple installation and layout times of various cables is avoided.