Belonging to manufacturing methods of plastic extruder screws, the invention relates to a manufacturing method of a halogen-free and glass fiber reinforced plastic-containing plastic extruder screw. The halogen-free and glass fiber plastic-containing extruder screw is manufactured by compounding an inner and an outer alloy material. The inner material provides screw strength and toughness performance, and the outer material has corrosion resistance, wear resistance and material transfer requirements. The extruder screw is a universal overall screw composed of a feeding section, a compression section and a metering section. The length of the compression section is between gradual change and abrupt change. The feeding section has a small diameter, an equal screw pitch and an equal screw arris groove depth. The first screw arris groove depth of the feeding section and the last screw arris groove depth are in a ratio of 3-7. The compression section has an equal screw pitch and a quasi gradual change screw arris groove depth. The metering section has a large diameter, an equal screw pitch and an equal screw arris groove depth. The conicity of a screw discharge end is 90 degrees. The screw contains at least a set of screw arrises. The screw length and the screw arris diameter are in a ratio of 20-50. The extruder screw provided in the invention has the advantages: wear resistance and high temperature corrosion resistance, as well as long service life.