At present, three-dimensional audio signals are mostly stored and played locally, coding compression of the audio signals is unavailable, or only each sound track is coded independently, code rate can be increased in a linear mode along with the number of the sound tracks, and data size of a audio file can be very large. Compression ratio can be greatly improved with a parameterization coding method, however, space information code rate can also be increased in a linear mode along with the number of the sound tracks, and distortion of the space direction sense of a three-dimensional audio and obvious reducing of the rebuilding effect of the three-dimensional audio can be caused by parameter quantification errors under the condition that the code rate is limited by a real-time rebroadcast bandwidth and capacity of a storage medium. According to the three-dimensional audio space parameter quantification method based on the perception characteristic, in order to solve the problems in the prior art, an uneven quantization table is generated by obtaining perception threshold values in different directions, and encoding rate of parameters is effectively reduced compared with a traditional even quantification table.