The invention provides an anti-slip shoe cover which comprises a shoe cover body, a welt and a sole; the sole is arranged on one side of the shoe cover body that is contacted with the ground; the welt is arranged on the other side of the shoe cover, which is opposite to the sole; the welt is provided with a welt adjusting structure; and spikes are arranged on the sole. The anti-slip shoe cover has the advantages that the design of an anti-slip part and the spikes has an obvious anti-slip effect, the sole is made of rubber material and the spikes are made of aluminum alloy material, so that the shoe cover is light to wear, and the welt adjusting structure provides convenience for a user to put on or take off the shoe cover.