The invention discloses a panel periphery connection structure. The panel periphery connection structure comprises two signal output layers formed on a substrate, insulation layers positioned on the signal output layers, a second electrode layer arranged on the uppermost insulation layer, and a first electrode layer positioned below one signal output layer, wherein the second electrode layer is conductively connected with the two signal output layers through a conductive through hole respectively; the first electrode layer is provided with an outer edge horizontally protruding from the surface of the signal output layers above the first electrode layer; and the second electrode layer is conductively connected with the outer edge of the first electrode layer through a peripheral conductive through hole. The invention further discloses a display device comprising the connection structure. Therefore, the image greening phenomenon of the display device caused by poor connection can be improved.