Method of manufacturing a self-sealing elastomer composition comprising at least a diene elastomer, a hydrocarbon resin having a given softening point and a liquid plasticizer, characterized in that it comprises the following successive steps: (a) the hydrocarbon resin is incorporated into the diene elastomer by mixing these components in a mixer at a temperature or up to a temperature called the 'hot mixing' temperature above the softening point of the hydrocarbon resin, in order to obtain a masterbatch; (b) the liquid plasticizer is incorporated into the masterbatch, by mixing all the ingredients together in the same mixer or in a different mixer, in order to obtain the self-sealing composition; and (c) said self-sealing composition is formed according to the required dimensions.