The invention discloses Chinese medicinal enteric capsules for treating medium-term and advanced tumors and chronic hepatitis B and a preparation method for the capsules. The capsules are prepared by processing a medicinal active ingredient prepared from dried toad skin and a medicinally acceptable carrier in a certain ratio, wherein the medicinal carrier consists of sodium carboxymethylcelluloseand starch. Compared with the prior art, the Chinese medicinal enteric capsules and the preparation method have the advantages that 60 percent ethanol is adopted for reflux extraction, so that the content of indole alkaloid and toad venom lactone which serve as active ingredients is improved, the curative effect is enhanced, the toxic or side effect of medicaments is reduced, the administration effect of a patient is remarkable, and the capsules are safe and convenient.