The invention relates to a compound cod-liver oil ointment as well as a preparation method and application thereof. The compound cod-liver oil ointment comprises the following raw materials in parts by weight: 80-120 parts of cod-liver oil, 35-65 parts of zinc oxide and 3.5-6.5 parts of ethacridine lactate. The compound cod-liver oil ointment has the effects of removing necrotic tissue, promoting granulation, converging, diminishing inflammation, reliving itching, clearing heat and reliving pain and promoting wound healing and has obvious curative effects of treating skin mucosa ulcer and sufferings and red swollen crissum. As a whole, the compound cod-liver oil ointment has the advantages that the curative effect is definite, use is convenient, acting is quick and the like, and is safe; no pain is generated; and the effective rate of the compound cod-liver oil ointment reaches 100%.