The invention provides an energetic perforating bullet holder for an oil and gas well, which is used for solving the problems that the traditional perforating bullet holder is easy to loosen and fall off in the underground transportation process and the burst height of a perforating bullet is nonadjustable. The energetic perforating bullet holder comprises a perforating bullet holder, wherein pressing and clamping pieces are symmetrically arranged above the perforating bullet holder; a clamping slot is arranged above the perforating bullet holder and provided with an elastic element; and the perforating bullet holder is internally provided with a boss. The perforating bullet holder is formed by pressing and pouring energetic material through a mould, and the energetic material is formed by mixing a composite explosive and at least one selected from light alloy powder and nonmetal powder. The energetic perforating bullet holder is simple in structure, strong in intercoordination and interconversion adaptability and low in cost; the structure is varied; synergistic perforating explosive cakes can be replaced, and the inside space of a bullet perforator can be saved; and the perforating bullet holder is internally provided with the boss so that the burst height of the perforating bullet can be controlled. The function of a composite explosive cake can be fully replaced, and the energetic perforating bullet holder is suitable for being applied to various perforating processes and perforating bullet types.