The invention discloses a takeoff-free feces automatic cleanup device, which comprises a fully automatic treater and a toilet stool, wherein the toilet stool is provided with a feces collection area, a urinating and defecating port, a hot water input pipe and a hot air input pipe; and the fully automatic treater comprises a machine shell, a feces discharge barrel, a negative pressure device, a hot water device, a hot air device and a control device, and the fully automatic treater is also provided with a packing device which is connected with the feces discharge barrel and can be used for packing feces and urine and sewage in a sealing mode; and the toilet stool is self-adaption briefs made of flexible shell fabric, the feces collection area is arranged at the crotch of the self-adaption briefs and is made of a soft waterproof material, and the fully automatic treater is also provided with a positive pressure device which can be used for inflating the self-adaption briefs so as to unfold the feces collection area to form an excretion space. The toilet stool disclosed by the invention can be worn by a user for a longer time, the user does not need the assistance of other people in defecation, and after defecation, sanification is simple, and the device has the advantages that the toilet stool is free from takeoff, is easy, convenient and comfortable to use and the like.