The invention provides an extrusion apparatus for removing bubbles, wherein the speed of the pressure change (delta P) of the interior space is improved. Bubbles adhered to the surface of panels are effectively removed by changing the volume of the interior space of an extrusion module and the temperature of the interior space. When the piston of a cylinder connected with the sealed extrusion module is in a reciprocating movement, the volume of the extrusion module is changed. The extrusion apparatus comprises an extrusion plate equipped with a plurality of through holes. Through the pressure change applied on a panel inside the extrusion module, the removal efficiency of bubbles is improved.