Provided is an air-conditioning bed, comprising a bed frame extending along a horizontal direction, a mattress arranged upon and supported to the bed frame, and a head panel arranged at an end portion of the bed frame. The mattress is associated with a first air conditioning system, thus to provide adjusted air to the area around the body of the user, thereby forming an air-conditioning area. The head panel is associated with a second air-conditioning system, thus to provide adjusted air to the area around the head of the user. Both the first and second air-conditioning systems comprise a thermoelectricity module having thermoelectricity apparatus.