The invention discloses Chinese compound preparation for treating liver injury and a preparation process thereof. The preparation is prepared from the following raw materials in part by weight: 10 to 20 parts of oriental wormwood, 10 to 20 parts of pericarpium citri reticulatae viride, 5 to 15 parts of medlar, 5 to 15 parts of raw rehmannia glutinosa, 5 to 15 parts of Codonopsis pilosula, 5 to 15parts of glossy privet fruit and 5 to 15 parts of Schisandra chinensis. The oriental wormwood having the effects of eliminating dampness, soothing liver and gall and promoting dieresis is used as a monarch medicine; pericarpium citri reticulatae virid is mainly used for relieving stagnant Qi and eliminating liver stagnation and is used as a minister medicine; the medlar and glossy privet fruit are used as assistant medicines for nourishing liver and tonifying kidney; and the medicines are combined to produce effects of protecting liver, removing jaundice, and tonifying liver and kidney and has remarkable effect on costalgia due to liver injury, jaundice and liver-qi depression, which are caused by antitubercular agents. The Chinese medicinal composition for treating liver injury, which isprepared by the invention, is simple process control, high in bioavailability, good in medicine effect, quick in treatment effect and low in cost.