The invention relates to a preparation method of wine, in particular to a preparation method of full-juice lichi dry wine. In the preparation method, lichi fresh fruit serves as a raw material of the full-juice dry wine, so the intrinsic fragrance of the lichi fruit is maintained, the natural value of the lichi fruit is preserved, the natural alcohol content of the lichi fruit is retained, and residual sugar with concentration of less than 4 g/L meets the national standard. The preparation method comprises the following operating steps of: (1) harvesting the lichi fresh fruit serving as the raw material; (2) removing shells and kernels; (3) juicing the lichi and adding sulfur dioxide into the juice; (4) clarifying; (5) performing alcoholic fermentation; (6) adding sulfur dioxide; (7) clarifying and separating; (8) refrigerating and ageing; and (9) degerming, filtering and bottling.