The invention discloses a seed production method of hybrid wheat Chuanmai 59, which comprises the following steps of: selecting parents; determining an optimal application period of a chemical hybridizing agent SQ-1; applying the chemical hybridizing agent in a spraying mode; setting isolation conditions; selecting the optimal seeding date, the optimal row ratio and the optimal sowing width of the parents; removing impurities; and pollinating. By selecting the optimal application period of the hybridizing agent, the optimal seeding date of the parents and the optimal row ratio of the parents, the usage and the using times of the hybridizing agent can be greatly reduced. Moreover, seeds of the high-yield, stable-yield and high-quality hybrid wheat Chuanmai 59 can be obtained without regulating the blooming period by hormone.