The invention provides a shell of an electronic device, comprising a transparent window member, a first shell member and a second shell member, wherein the window member is a glass panel comprising an inner surface and a side wall, the first shell member and the second shell member are respectively formed in an injection molding way and are combined with the window member, the first shell member is combined with the side wall of the window member, and the second shell member is combined with the first shell member and is combined with partial area of the inner surface of the window member. The invention further provides a manufacturing method of the shell of an electronic device.