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发明授权
CN102018667B 一种咪唑类抗真菌皮肤擦拭剂及其制备方法 有权 转让

一种咪唑类抗真菌皮肤擦拭剂及其制备方法
摘要：
本发明公开了一种咪唑类抗真菌皮肤擦拭剂，其特征在于主要由下列重量百分比的原料组成：咪唑类抗真菌药物0.1%～5%、表面活性剂1%～5%、皮肤渗透剂2%～4%、药物缓释剂3%～5%、水溶性助溶剂30%～50%、增稠剂3%～7%、盐类0.5%～1%、抗静电剂0.2%～0.5%、着色剂0.1%～0.3%、营养剂0.7%～1.5%、余量为蒸馏水。本发明的皮肤擦拭剂粘度小、性质稳定，能够透过皮肤进入血液循环，释放速度稳定，对治疗由真菌引起的真菌性青春痘、头屑等有持续、强有力的治疗效果。本发明还提供了上述咪唑类抗真菌皮肤擦拭剂的制备方法。
摘要（英）：

The invention discloses an imidazoles antifungal skin wiping agent which is characterized by comprising the following materials in percent by weight: 0.1-5% of imidazoles antifungal drug, 1-5% of surface active agent, 2-4% of skin penetrant, 3-5% of drug release agent, 30-50% of water-soluble cosolvent, 3-7% of thickener, 0.5-1% of salts, 0.2-0.5% of antistatic agent, 0.1-0.3% of coloring agent, 0.7-1.5% of nutrition agent and the balance of distilled water. The skin wiping agent has the advantages of little viscosity, stable property and stable releasing speed, can enter blood circulation through the skin and has continuous and strong effect on treating fungoid whelk, scurf and the like caused by fungus. The invention also provides a preparation method of the imidazoles antifungal skin wiping agent.

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