The invention discloses a method for adjusting derivation of a main wheel of a hoister. The method comprises a process of measuring distances from a driving shaft to a vertical reference line and to a horizontal reference line and distances from a driven shaft to the vertical reference line and to the horizontal reference line and a process of comparing detection data with standard data and correcting and adjusting the detection data, wherein the standard data are as follows: the centricity derivation ranges of driving and driven delivery wheels are less than 0.04mm; the axiality derivation ranges of the driving and driven shafts are less than 2mm; a horizontal error range of the driving shaft is less than 1mm; the horizontal error range of the driven shaft is less than 2mm; the central point derivation ranges of the driving and driven shafts and the hoister are less than 2mm; and the verticality error ranges of the driving and driven shafts are less than 1.5mm. In the invention, whether the main wheel derivates or not can be judged conveniently and quickly and whether the hoister is in a good operation state can be detected easily. The method has a great instructive significance for installation, modulation and overhauling and can greatly save the installation and modulation time of the hoister and effectively prolong the service life of the hoister.