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CN101914500A 基因重组的H9N1亚型禽流感病毒及其应用 无效 - 驳回

基因重组的H9N1亚型禽流感病毒及其应用
摘要：
本发明涉及一种基因重组的H9N1亚型禽流感病毒，以及该病毒在制备预防H9N2亚型禽流感病毒感染的灭活疫苗中的应用，该病毒已于2009年8月3日保藏于中国典型培养物保藏中心，保藏编号为CCTCC V200913，包括具有H9N2亚型禽流感病毒A/Chicken/Hubei/C1/2007(H9N2)的HA基因以及H1N1流感病毒A/PR/8/34(H1N1)的7个内部基因PB2、PB1、PA、NP、NA、M和NS，上述的基因重组的H9N1亚型禽流感病毒在制备预防H9N2亚型禽流感病毒感染的灭活疫苗的应用以及H9N1亚型禽流感灭活疫苗在区分免疫(H9N1)或野毒(H9N2)感染状况中的应用。
摘要（英）：

The invention relates to a gene-recombined H9N1 subtype avian influenza virus and application thereof to preparing inactivated vaccines for preventing infection of an H9N2 subtype avian influenza virus. The virus is preserved in the China Center for Type Culture Collection (CCTCC) in August 3rd, 2009, and the preservation number is CCTCC V200913. The virus comprises an HA gene containing the H9N2 subtype avian influenza virus A/Chicken/Hubei/C1/2007 (H9N2) and 7 internal genes (PB2, PB1, PA, NP, NA, M and NS) containing the H1N1 influenza virus A/PR/8/34 (H1N1). The invention provides the application of the H9N1 subtype avian influenza virus to preparing the inactivated vaccines for preventing infection of the H9N2 subtype avian influenza virus, and the application of the H9N1 subtype avian influenza inactivated vaccines to distinguishing the immunity (H9N1) or field strain (H9N2) infection condition.

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