The invention discloses an FPGA-based enhanced serial port and working method thereof. The FPGA (Field Programmable Gate Array) is taken as hardware, and the serial port is constructed in the FPGA by using an HDL language; the Baud rate, check mode, data length and the like of the serial port are conveniently and quickly configured by an external program, and the serial port automatically receives and sends data; the size of a cache for transceiving the data only depends on the scale of the FPGA; and a plurality of serial ports can be generated by multiplexing through simple operation, and the processing time and hardware resource of a main program are not occupied. For the main program, it is similar to operation on an external storage, so the main program is freed from the frequently interruption or query operation, the running efficiency of the main program is improved, the stability of the system is improved and the transplantability and the expandability of software are improved.