The invention provides a catalyst used for the hydro-conversion of a hydrocarbon. The catalyst comprises at least two types of silicon oxide-aluminum oxide of which the difference value of an N value is between 0.02 and 0.2, Y type zeolite of which the degree of crystallization is 60 percent, at least one type of VIB family metal component and at least one type of VIII family metal component, wherein based on the catalyst, the silicon oxide-aluminum oxide accounts for 1 to 75 weight percent and the Y type zeolite accounts for 0.1 to 65 weight percent; based on the oxide, the VIB family metal component accounts for 5 to 40 weight percent and the VIII family metal component accounts for 1 to 15 weight percent; and N=P1/P2, wherein P1 is the peak area of place of which the chemical shift is 60+/-0.1-0.2 ppm in a solid 27Al NMR spectrogram of the silicon oxide-aluminum oxide and P2 is the peak area of a place of which the chemical shift is 5+/-0.1-0.2 ppm in the solid 27Al NMR spectrogram of the silicon oxide-aluminum oxide. Compared with conventional catalysts, the catalyst provided by the invention has higher selectivity of isomerization reaction and higher hydrocarbon oil hydro-conversion activity.