The present invention discloses an oral medicine for preventing and curing canine enteric bacterial disease, which is composed of the following raw material in ratio by weight: 1-1.2g of lactobacillin sheet which the concentration is 5*108 cfu/g, 0.8-1g of dangshen, 0.8-1g of white atractylodes rhizome, 0.6-0.8g of Scutellaria baicalensis, 0.8-1g of radix sophorae flavescentis, 0.8-1g of Coptis chinensis, 0.8-1g of Poria cocos, 0.6-0.8g of Chinese yam, 0.6-0.8g of white hyacinth Bean and 0.4-0.6g of liquorice. The raw materials are mixed, smashed, ground, evenly stirred and mixed. The oral medicine for preventing and curing canine enteric bacterial disease provided by the present invention can inhibit the growth and breeding of germs and bacteria harmful to dog body health, has the effect of resisting bacteria and diseases, and has stable curative efficacy.