The invention discloses a interphone high-power active antenna, which comprises a DC/AC circuit combiner, an active antenna amplifier and an antenna, wherein the DC/AC circuit combiner and the active antenna amplifier are respectively provided with high-frequency signal ends and DC power supply ends, the active antenna amplifier is arranged on the antenna, and signals and power supplies between the DC/AC circuit combiner and the active antenna amplifier are simultaneously transmitted through coaxial cables. The invention has the advantages that the active antenna amplifier of the novel interphone antenna is arranged on the antenna, the large-power signals are transmitted onto the antenna without consumption, and highest receiving and sending efficiency can be obtained at an antenna port, so the transmission efficiency can be improved, the output power can reach 35 w, the receiving sensitivity can be higher than or equal to 40 DB, and the invention can be applicable to longer communication distance. On the basis of the original hand-hold interphone, the invention can be expanded into an on-vehicle antenna and a base station antenna, and the transmission effect of the invention can be comparable to that of the on-vehicle antenna and the base station antenna.