The invention relates to underground construction equipment, in particular to multi-spindle drilling and stirring equipment. A hydraulic middle-drive retractable multi-spindle drilling and stirring device comprises a middle-drive hydraulic power source, a drill stem, a bit body, a pipeline system, a lifting device and a connecting frame, wherein a guide device is arranged on the connecting frame;the drill stem is a hollow retractable drill stem; the upper end of the drill stem is connected with the lifting device; and the drill stem can move up and down on a middle drive hydraulic power headand transmit power. A connecting frame is arranged on the hydraulic power source. The connecting frame and the lifting device are connected by a steel wire rope. The effective working depth of the multi-spindle drilling and stirring device is increased and the drive distance is shortened, so that the device can be reliably used for drilling deep stratums.