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发明公开
CN101768154A 一种新的依潘立酮的制备方法 无效 - 撤回

一种新的依潘立酮的制备方法
摘要：
本发明提供一种新的伊潘立酮制备方法，该发明包括使6-氟-3-(4-哌啶基)-1，2-苯并异噁唑盐酸盐与1-[4-(3-氯丙氧基)-3-甲氧苯基]乙基酮在无机碱性水液中反应得到伊潘立酮。该方法收率高、成本低，对操作人员和环境没有不利影响，非常适合于工业化大生产。
摘要（英）：

The invention provides a new preparation method of iloperidone, comprising leading 6 - F -3 - (4 - piperidinyl) -1,2 - benzisoxazole hydrochloride and 1 - [4 - (3 - chloropropoxy) -3 - methoxyphenyl] ethyl ketone to react in the inorganic alkaline water solution to obtain the iloperidone. The advantages of the invention are as follows: the method has high yield, low cost, no adverse effects for operators and environment, and is very suitable for industrial mass production.

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