The invention discloses a method for refining Valsartan containing higher isomer impurity, namely Valsartan containing more than 10% (HPLC detection peak area method) of N isomer is refined by adopting butanone or the mixture solvent of butanone and esters and ethers, the N isomer can be remarkably reduced to about 1.0%, and the yield can be as high as more than 50%.