The invention discloses a multi-cell transfusion system. The system comprises a container, a cover body, at least one rubber mat, at least one tabletting and at least one hollow accommodating cavity, wherein the container is used for accommodating a first medium; the cover body is sealed and combined with the container; the rubber mat is arranged in the cover body; the tabletting is located abovethe rubber mat and compacts the rubber mat to seal the cover body; and the hollow accommodating cavity for accommodating a second medium is arranged in the cover body. According to the multi-cell transfusion system, the double-cell or multi-cell medicine-charging can be realized on a plastic bottle, and the medicine can be fast and conveniently mixed before using, thereby the stability of the medicine and the safety of administration are greatly improved; and the invention has the characteristics of low production cost, safety and reliability, and the like.