The invention provides a method for inspecting quality of indigowoad leaf Chinese medicament, which comprises the following steps: processing indigowoad leaves by sample preprocessing means such as water extraction, ethanol processing, extraction with ethyl acetate and water saturated n-butyl alcohol sequentially, concentration an volume fixation; obtaining a finger-print of the indigowoad leaf Chinese medicament by electron spray mass spectrometry; measuring the nucleoside content and purine content of the indigowoad leaf Chinese medicament by high performance liquid chromatography; and measuring the total flavonoid content of the indigowoad leaf Chinese medicament by UV-VIS spectrophotometry, and integrating the finger-print and the measure data of the content to evaluate the quality ofthe indigowoad leaf Chinese medicament. The quality inspection method is accurate, quick, convenient and effective.