The invention relates to an infrared target simulator with infrared interference, which comprises a shell, wherein four sets of mutually parallel infrared simulating light tubes are arranged in the shell and ranged in two lines and two rows; two sets of infrared simulating light tubes positioned in a line or a row are interference source simulating light tubes, and another two sets of infrared simulating light tubes are target simulating light tubes which are fixedly installed in the shell; the interference source simulating light tubes are rotatably arranged in the shell by hinges, and rotating shafts of the hinges on the two interference source simulating light tubes are mutually perpendicular; and drive devices for driving the interference source simulating light tubes to swing to and fro around the rotating shafts of the hinges are arranged outside the interference source simulating light tubes. The infrared target simulator with infrared interference can simulate an infinite distance target and a super-near distance target and simulate an interference source of motion of bait center separation, viewing field traversing, and the like.