The invention discloses a packaging bottle produced by utilizing unsaturated polyester resin and a manufacturing method thereof. The packaging bottle comprises an inner bottle and an inner-bottle covering bodies, wherein the inner bottle is a liner; the inner-bottle covering bodies are unsaturated polyester resin covering a surface layer of the liner; the inner bottle and the inner-bottle covering bodies are a whole which is indivisible and completely integrated and has beautiful appearance and artistic style; not less than one layer of the inner-bottle covering bodies covers an inner bottle body; and each layer of the covering bodies has a different artistic expression form and a unique appearance style.