The invention discloses a technique for eliminating deviations between object space control points and image navigation in digital photogrammetry, which is used for the digital photogrammetry taking CCD and CMOS as imaging target surfaces and comprises the following steps that: (1) a pre-labeled mark consists of a central region and a surrounding region with the same geometric center and different optical characteristics; (2) an imaging device keeps the edge of an imaging target surface pixel to be parallel with the edge of the pre-labeled mark when acquiring a digital image; and (3) the deviations between the digital image acquired by the imaging device and actual mark position parameters are corrected and computed. The technique can effectively eliminate the matching errors between the control points on the image and the actual ground control points in the digital photogrammetry.