The invention discloses a plug-picking device for a cassette bottle filling machine, comprising a servo motor, a gear transmission mechanism, a plug-picking plate, a center shaft, a rotating shaft and a lifting mechanism; an output shaft of the servo motor is connected with the rotating shaft through the gear transmission mechanism; the center shaft is arranged in the rotating shaft; the plug-picking plate is fixed at the upper end of the center shaft; and the bottom end of the center shaft is connected with the lifting mechanism. The plug-picking device for the cassette bottle filling machine has simple and compact structure, low cost, simple and convenient installation, high action precision and capability of improving the working efficiency of an entire machine and the quality of products.