The invention discloses a method for the surface plasmon resonance detection of medicinal methamphetamine, which belongs to the technical field of detection. A methamphetamine molecule recognizing and sensing chip is used as a sensor chip of a surface plasmon resonance detector, so that when a sample to be detected passes through the surface of the sensor chip, the surface plasmon resonance detector can detect the change of the light intensity of totally reflected light at the position of the interface between the sample to be detected and the molecule recognizing and sensing chip to directly determine the methamphetamine content of the sample to be detected. The detection method has the characteristics of severe environment resistance, high selectivity, quick response and simple and convenient operation and has improved sensitivity and reduced detection cost.