The invention provides an aseptic filling valve, which comprises a valve body and a valve rod with a valve plug, and is provided with a lever driving the valve rod to lift; the lateral surface of the valve body is provided with a lever extending-in opening, and the lever extends into the valve body from the lateral surface of the valve body; and the aseptic filling valve is also provided with a flexible diaphragm which is in seal fit with the lever and encloses the valve body on the lever extending-in position. The aseptic filling valve can realize constant aseptic obstruction under the working condition of long-time frequent opening and closing so as to improve the safety of aseptic filling production; moreover, distances to a lever fulcrum are different, and the rotation amplitudes of the lever are different, so that manufacturers have more options to flexibly adopt an aseptic obstruction implementation proposal with economy, high reliability and easy realization according to actual conditions.