The invention discloses a flue gas desulfurization process for comprehensively utilizing sintering flue gas. In the flue gas desulfurization process, a desulfurizing tower for absorbing sulfur dioxideand a regeneration tower for reclaiming desulphurization rich solution discharged by the desulfurizing tower are arranged; the sintering flue gas discharged by a sintering machine is conveyed to theregeneration tower, the sintering flue gas taken as a heat source indirectly heats the desulphurization rich solution in the regeneration tower to decompose the sulfur dioxide in the desulphurizationrich solution, and an absorption liquid obtained after the desulphurization rich solution is regenerated is conveyed to the desulfurizing tower; and the discharged sintering flue gas in the regeneration tower is subjected to washing, dedusting and temperature reduction and then is sent into the desulfurizing tower, the sintering flue gas is subjected to cyclical absorption and desulphurization by the absorption liquid to obtain purified gas, and the purified gas is exhausted into atmosphere. The flue gas desulfurization process fully makes use of abandon resources, has less energy consumption,and low cost and can effectively reduce the occurrence of the phenomenon of flue gas condensation.