The invention relates to a pharmaceutical composition for curing the thermal damage of mammal or human and a preparation method thereof. The pharmaceutical composition comprises the following componenThe invention relates to a pharmaceutical composition for curing the thermal damage of mammal or human and a preparation method thereof. The pharmaceutical composition comprises the following components by the total weight: 2-12 percent of Chinese wax and 88-98 percent of sesame oil extract including green tea leaves, crinis carbonisatus, lithospermum, radix rehmanniae recen and coptis root, and tts by the total weight: 2-12 percent of Chinese wax and 88-98 percent of sesame oil extract including green tea leaves, crinis carbonisatus, lithospermum, radix rehmanniae recen and coptis root, and the green tea leaves, the crinis carbonisatus, the lithospermum, the radix rehmanniae recen and the coftis root respectively account for 1-8 percent of the total weight of the sesame oil extract accordhe green tea leaves, the crinis carbonisatus, the lithospermum, the radix rehmanniae recen and the coftis root respectively account for 1-8 percent of the total weight of the sesame oil extract according to the weight of the dry decoction pieces. The invention has the advantages of quick pain relieving, short treatment course and low formation rate of cicatrix; and the invention does not select thing to the weight of the dry decoction pieces. The invention has the advantages of quick pain relieving, short treatment course and low formation rate of cicatrix; and the invention does not select the toxic and addictive drugs from the aspect of medication safety and has proper price.e toxic and addictive drugs from the aspect of medication safety and has proper price.