The invention relates to a nutrition food with oxidation resistance function and a preparation method thereof, belonging to the field of functional foods. The functional nutrition food is mainly prepared by medicine and food dual-purpose materials according to the following parts by weight: 1-5 of Shizhu panax, 1-5 of chrysanthemum, 3-9 of sessileflower acanthopanax barks, 3-9 of tuckahoe, 3-9 of niger seeds, 1-5 of peach kernels, 3-9 of bee pollen, 1-5 of white fungus, 1-5 of blackfungus, 1-5 of monkey's head mushrooms, 2-8 of mushrooms, 1-5 of grape pips, 0.5-1.5 of lycopene and 0.5-1.5 of royal jelly. Results of experiments on animal and human prove that the nutrition food has obvious oxidation resistance function and can also improve the immunization, thereby being suitable for the people needing oxidation resistance, but not suitable for children.