The invention discloses a drug for treating rheumatoid bone disease. A formulatin of the drug for treating the rheumatoid bone disease comprises raw material medicines of atractylis lancea, fructus psoraleae and copperas which are in proportion by weight of 1.5 to 2.5:0.8 to 1.2:0.8 to 1.2. According to mixture ratio, the atractylis lancea and the fructus psoraleae are weighed, and are fried respectively by semen sesami nigrum; the semen sesami nigrum is screened out; the mixture is ground into fine powders; the fine powders are sifted; the copperas is added with millet vinegar and is calcined; after calcination, the mixture is ground into the fine powders; the fine powders are sifted; and finally, the atractylis lancea, fructus psoraleae and copperas fine powders which are subjected to screening treatment are evenly mixied and prepared to obtain a product. The product for treating the rheumatoid bone disease has little drug compatibility, a simple preparation method, easy popularization and implementation, remarkable treatment effect, short treatment course, low cost, and no toxicity and no side effect, and can radically cure various symptoms of the rheumatoid bone disease; the healing rate reaches as high as 98 percent; and the effective rate is 100 percent.